Neuronal MD2 induces long-term mental impairments in septic mice by facilitating necroptosis and apoptosis

Sepsis-associated encephalopathy (SAE) is a complication of sepsis with high morbidity rates. Long-lasting mental health issues in patients with SAE result in a substantial decrease in quality of life. However, its underlying mechanism is unclear, and effective treatments are not available. In the c...

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Bibliographic Details
Main Authors: Zhongmin Fan, Hongwei Ma, Yi Li, You Wu, Jiajia Wang, Lize Xiong, Zongping Fang, Xijing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.884821/full