Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT

Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT

The nephrotoxicity of Fructus Psoraleae, an effective traditional Chinese medicine for vitiligo treatment, has been reported. As one of the main toxic components in Fructus Psoraleae, bavachin (BV) was considered to be related to Fructus Psoraleae-caused adverse outcomes, but the direct evidence and...

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Bibliographic Details
Main Authors: Yu-Hao Ni, Hui-Fang Deng, Lei Zhou, Cong-Shu Huang, Ning-Ning Wang, Lan-Xin Yue, Gao-Fu Li, Hui-Jing Yu, Wei Zhou, Yue Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
bavachin
ER stress
EMT
renal fibrosis
ginsenoside Rb1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.872474/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.872474/full

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