Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis

Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis

Schistosomiasis is a neglected tropical disease affecting more than 200 million people worldwide. Chemotherapy relies on one single drug, praziquantel, which is safe but ineffective at killing larval stages of this parasite. Furthermore, concerns have been expressed about the rise in resistance agai...

Full description

Bibliographic Details
Main Authors: Bernardo Pereira Moreira, Michael H. W. Weber, Simone Haeberlein, Annika S. Mokosch, Bernhard Spengler, Christoph G. Grevelding, Franco H. Falcone
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
schistosomiasis
protein kinase inhibitors
drug repurposing
de novo drug repurposing
AP-SMALDI MSI
Online Access:https://www.mdpi.com/1420-3049/27/4/1414

Internet

https://www.mdpi.com/1420-3049/27/4/1414

Similar Items