Acenocoumarol Pharmacogenetic Dosing Algorithm versus Usual Care in Patients with Venous Thromboembolism: A Randomised Clinical Trial

Patients with venous thromboembolism (VTE) require immediate treatment with anticoagulants such as acenocoumarol. This multicentre randomised clinical trial evaluated the effectiveness of a dosing pharmacogenetic algorithm versus a standard-of-care dose adjustment at the beginning of acenocoumarol t...

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Bibliographic Details
Main Authors: Hoi Yan Tong, Alberto M. Borobia, Manuel Quintana-Díaz, Sara Fabra, Manuel González-Viñolis, Carmen Fernández-Capitán, María A. Rodriguez-Dávila, Alicia Lorenzo, Ana María López-Parra, Nuria Ruiz-Giménez, Francisco Abad-Santos, Carmen Suarez, Olga Madridano, Jorge Francisco Gómez-Cerezo, Pilar Llamas, Carlos Baeza-Richer, Eduardo Arroyo-Pardo, Antonio J. Carcas, The PGX-ACE Spanish Investigators Group
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/13/2949