Acenocoumarol Pharmacogenetic Dosing Algorithm versus Usual Care in Patients with Venous Thromboembolism: A Randomised Clinical Trial

Acenocoumarol Pharmacogenetic Dosing Algorithm versus Usual Care in Patients with Venous Thromboembolism: A Randomised Clinical Trial

Patients with venous thromboembolism (VTE) require immediate treatment with anticoagulants such as acenocoumarol. This multicentre randomised clinical trial evaluated the effectiveness of a dosing pharmacogenetic algorithm versus a standard-of-care dose adjustment at the beginning of acenocoumarol t...

Full description

Bibliographic Details
Main Authors:	Hoi Yan Tong, Alberto M. Borobia, Manuel Quintana-Díaz, Sara Fabra, Manuel González-Viñolis, Carmen Fernández-Capitán, María A. Rodriguez-Dávila, Alicia Lorenzo, Ana María López-Parra, Nuria Ruiz-Giménez, Francisco Abad-Santos, Carmen Suarez, Olga Madridano, Jorge Francisco Gómez-Cerezo, Pilar Llamas, Carlos Baeza-Richer, Eduardo Arroyo-Pardo, Antonio J. Carcas, The PGX-ACE Spanish Investigators Group
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Journal of Clinical Medicine
Subjects:	pharmacogenetics acenocoumarol venous thromboembolism clinical trial
Online Access:	https://www.mdpi.com/2077-0383/10/13/2949

Similar Items

Efficiency and effectiveness of the use of an acenocoumarol pharmacogenetic dosing algorithm versus usual care in patients with venous thromboembolic disease initiating oral anticoagulation: study protocol for a randomized controlled trial
by: Carcas Antonio J, et al.
Published: (2012-12-01)

A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study
by: Angela Roco, et al.
Published: (2020-04-01)

The VKORC1 and CYP2C9 gene variants as pharmacogenetic factors in acenocoumarol therapy in Serbian patients - consideration of hypersensitivity and resistance
by: Rakićević Ljiljana, et al.
Published: (2022-01-01)

Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol
by: HU Bachmann
Published: (2004-06-01)

Incidence and cost of bleeding events requiring hospitalization in patients with atrial fibrillation treated with acenocoumarol in Greece
by: Georgia Kourlaba, et al.
Published: (2021-05-01)

Healthcare resources and costs associated with nonvalvular atrial fibrillation in Spain: apixaban versus acenocoumarol
by: Josep Comin Colet, et al.
Published: (2023-07-01)

Successful outcome with outpatient acenocoumarol therapy for echocardiographically visible pulmonary thrombus
by: Karanam Gowrinath, et al.
Published: (2021-01-01)

OPINION SURVEY OF THE CARDIOLOGISTS IN BULGARIA REGARDING THERAPY WITH ACETYLSALICYLIC ACID, CLOPIDOGREL AND ACENOCOUMAROL IN PATIENTS UNDERGOING DENTAL EXTRACTIONS
by: Atanaska Dinkova, et al.
Published: (2017-10-01)

Better stability of acenocoumarol compared to warfarin treatment in one-year observational, clinical study in patients with nonvalvular atrial fibrillation
by: Lejla Burnazović-Ristić, et al.
Published: (2011-02-01)

OPINION SURVEY OF THE GENERAL PRACTITIONERS IN BULGARIA REGARDING THERAPY WITH ACETYLSALICYLIC ACID, CLOPIDOGREL AND ACENOCOUMAROL IN PATIENTS UNDERGOING DENTAL EXTRACTIONS
by: Atanaska Dinkova, et al.
Published: (2017-11-01)

Acenocoumarol, an Anticoagulant Drug, Prevents Melanogenesis in B16F10 Melanoma Cells
by: Hyunju Han, et al.
Published: (2023-04-01)

Comparison of Anticoagulation Quality between Acenocoumarol and Warfarin in Patients with Mechanical Prosthetic Heart Valves: Insights from the Nationwide PLECTRUM Study
by: Danilo Menichelli, et al.
Published: (2021-03-01)

The Association Between Long-Term Acenocoumarol Treatment and Vitamin D Deficiency
by: Jolanta Sawicka-Powierza, et al.
Published: (2018-05-01)

A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population.
by: Hoi Y Tong, et al.
Published: (2016-01-01)

Acenocoumarol Exerts Anti-Inflammatory Activity via the Suppression of NF-κB and MAPK Pathways in RAW 264.7 Cells
by: Hyun-Ju Han, et al.
Published: (2023-02-01)

An acenocoumarol dosing algorithm using clinical and pharmacogenetic data in Spanish patients with thromboembolic disease.
by: Alberto M Borobia, et al.
Published: (2012-01-01)

Principles of pharmacogenetics and pharmacogenomics /
by: Altman, Russ B. 205766, et al.
Published: (2012)

Genotype-phenotype correlations in patients treated with acenocoumarol / Corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol
by: Militaru Florentina Claudia, et al.
Published: (2014-09-01)

Application of pharmacogenetics in oncology
by: Nelly N. Miteva-Marcheva, et al.
Published: (2020-08-01)

Pharmacogenetics from ethno-cultural perspectives
by: Chee Ng, et al.
Published: (2010-12-01)

Establishment of a Pharmacogenetics Service Focused on Optimizing Existing Pharmacogenetic Testing at a Large Academic Health Center
by: Amy L. Pasternak, et al.
Published: (2020-10-01)

Knowledge and attitude regarding pharmacogenetics among formerly pregnant women in the Netherlands and their interest in pharmacogenetic research
by: Aizati N. A. Daud, et al.
Published: (2017-04-01)

Developments in pharmacogenetics, pharmacogenomics, and personalized medicine
by: Francisco Abad-Santos, et al.
Published: (2024-02-01)

Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity
by: Stefan Stewart, et al.
Published: (2023-10-01)

Pharmacogenetics of antidepressants
by: Concetta eCrisafulli, et al.
Published: (2011-02-01)

Pharmacogenetic Testing: A Tool for Personalized Drug Therapy Optimization
by: Kristina A. Malsagova, et al.
Published: (2020-12-01)

The Pharmacogenetics of Treatment with Quetiapine
by: María Ortega-Ruiz, et al.
Published: (2022-07-01)

Pharmacogenetics of antidepressant drugs: An update
by: Crisafulli Concetta, et al.
Published: (2014-01-01)

Pharmacogenetics of breast cancer : towards the individualization of therapy /
by: Leyland-Jones, Brian
Published: (2008)

Bosentan and oral anticoagulants in HIV patients: what we can learn of cases reported so far
by: José Antonio Morales-Molina, et al.
Published: (2011-10-01)

Pharmacogenetics of hypoglycemic agents
by: Irina Vladimirovna Kononenko, et al.
Published: (2015-12-01)

The pharmacogenetics of cardiovascular drugs
by: Stanković Sanja, et al.
Published: (2014-01-01)

Ten Years of Experience Support Pharmacogenetic Testing to Guide Individualized Drug Therapy
by: María Celsa Peña-Martín, et al.
Published: (2022-01-01)

The concept of gene is in crisis. Does it affect pharmacogenetics and pharmacogenomics?
by: Miriam Falkenberg, et al.
Published: (2006-09-01)

Introducing Pharmacogenetics and Personalized Medicine via a Weblog
by: Kaitlin Bova, et al.
Published: (2014-01-01)

The utility of pharmacogenetic testing to support the treatment of bipolar disorder
by: Ielmini M, et al.
Published: (2018-03-01)

Pharmacogenetics: Knowledge assessment amongst Syrian pharmacists and physicians
by: Lina Albitar, et al.
Published: (2021-10-01)

Pharmacogenetics Update on Biologic Therapy in Psoriasis
by: Ester Muñoz-Aceituno, et al.
Published: (2020-12-01)

Pharmacogenetics of Donepezil and Memantine in Healthy Subjects
by: María C. Ovejero-Benito, et al.
Published: (2022-05-01)

Pharmacogenetics and its clinical applications in opioid therapy
by: Caterina Aurilio, et al.
Published: (2008-12-01)