Vitamin A- and D-Deficient Diets Disrupt Intestinal Antimicrobial Peptide Defense Involving Wnt and STAT5 Signaling Pathways in Mice

Vitamin A- and D-Deficient Diets Disrupt Intestinal Antimicrobial Peptide Defense Involving Wnt and STAT5 Signaling Pathways in Mice

Vitamin A and D deficiencies are associated with immune modulatory effects and intestinal barrier impairment. However, the underlying mechanisms remain unclear. C57BL/6J mice were fed either a diet lacking in vitamin A (VAd), vitamin D (VDd) or a control diet (CD) for 12 weeks. Gut barrier function,...

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Bibliographic Details
Main Authors: Louisa Filipe Rosa, Patricia P. Petersen, Lisa F. Görtz, Iris Stolzer, Valentina Kaden-Volynets, Claudia Günther, Stephan C. Bischoff
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Nutrients
Subjects:
vitamin A
vitamin D
antimicrobial peptides
gut barrier
Wnt signaling pathway
Jak/STAT
Online Access:https://www.mdpi.com/2072-6643/15/2/376

Internet

https://www.mdpi.com/2072-6643/15/2/376

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