Infection via mosquito bite alters Zika virus tissue tropism and replication kinetics in rhesus macaques
Vector saliva can affect infectivity and pathogenesis of vector-borne viruses, but this hasn’t been studied for Zika virus infection. Here, Dudley et al. show that mosquito-mediated Zika infection of macaques results in altered replication kinetics and greater sequence heterogeneity.
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-02222-8 |