NADPH Oxidase Mediates Oxidative Stress and Ventricular Remodeling through SIRT3/FOXO3a Pathway in Diabetic Mice

NADPH Oxidase Mediates Oxidative Stress and Ventricular Remodeling through SIRT3/FOXO3a Pathway in Diabetic Mice

Oxidative stress and mitochondrial dysfunction are important mechanisms of ventricular remodeling, predisposed to the development of diabetic cardiomyopathy (DCM) in type 2 diabetes mellitus. In this study, we have successfully established a model of type 2 diabetes using a high-fat diet (HFD) in co...

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Bibliographic Details
Main Authors: Jiuchun Qiu, Daiqi Liu, Pengsha Li, Lingling Zhou, Lu Zhou, Xing Liu, Yue Zhang, Meng Yuan, Gary Tse, Guangping Li, Tong Liu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
NADPH oxidase
oxidative stress
diabetic cardiomyopathy
Online Access:https://www.mdpi.com/2076-3921/11/9/1745

Internet

https://www.mdpi.com/2076-3921/11/9/1745

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