Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.

The influenza virus PB1-F2 is an 87-amino acid mitochondrial protein that previously has been shown to induce cell death, although the mechanism of apoptosis induction has remained unclear. In the process of characterizing its mechanism of action we found that the viral PB1-F2 protein sensitizes cel...

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Bibliographic Details
Main Authors: Dmitriy Zamarin, Adolfo García-Sastre, Xiaoyao Xiao, Rong Wang, Peter Palese
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0010004