Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage
Cartilaginous structures are at the core of embryo growth and shaping before the bone forms. Here we report a novel principle of vertebrate cartilage growth that is based on introducing transversally-oriented clones into pre-existing cartilage. This mechanism of growth uncouples the lateral expansio...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/25902 |