The Features of Checkpoint Receptor—Ligand Interaction in Cancer and the Therapeutic Effectiveness of Their Inhibition

The Features of Checkpoint Receptor—Ligand Interaction in Cancer and the Therapeutic Effectiveness of Their Inhibition

To date, certain problems have been identified in cancer immunotherapy using the inhibition of immune checkpoints (ICs). Despite the excellent effect of cancer therapy in some cases when blocking the PD-L1 (programmed death-ligand 1) ligand and the immune cell receptors PD-1 (programmed cell death p...

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Bibliographic Details
Main Authors: Anna Kuzevanova, Natalya Apanovich, Danzan Mansorunov, Alexandra Korotaeva, Alexander Karpukhin
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
immune checkpoint
expression
therapy
target
immune response
Online Access:https://www.mdpi.com/2227-9059/10/9/2081

Internet

https://www.mdpi.com/2227-9059/10/9/2081

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