Abrogating ALIX Interactions Results in Stuttering of the ESCRT Machinery

Endosomal sorting complexes required for transport (ESCRT) proteins assemble on budding cellular membranes and catalyze their fission. Using live imaging of HIV virions budding from cells, we followed recruitment of ESCRT proteins ALIX, CHMP4B and VPS4. We report that the ESCRT proteins transiently...

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Bibliographic Details
Main Authors: Shilpa Gupta, Mourad Bendjennat, Saveez Saffarian
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/9/1032