MicroRNA-related cofilin abnormality in Alzheimer's disease.

Rod-like structures composed of actin and the actin-binding protein cofilin are found in Alzheimer's disease (AD) patients. However, the mechanisms underlying formation of these structures and their pathological consequences are still largely unknown. We found that microRNAs 103 and 107 repress...

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Bibliographic Details
Main Authors: Jiaqi Yao, Tom Hennessey, Alex Flynt, Eric Lai, M Flint Beal, Michael T Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3002958?pdf=render