The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis

The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, and innate immune responses and inflammation are known to affect the course of disease. Interferon (IFN) signaling in particular is critical for modulating inflammation-associated diseases including CRC. While the effects...

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Bibliographic Details
Main Authors: Bhesh Raj Sharma, Rajendra Karki, Balamurugan Sundaram, Yaqiu Wang, Peter Vogel, Thirumala-Devi Kanneganti
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
interferons
IRF9
colitis
colorectal cancer
tumorigenesis
IL-6
Online Access:https://www.mdpi.com/2072-6694/14/4/919

Internet

https://www.mdpi.com/2072-6694/14/4/919

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