Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism

Blood vessel formation is an important initial step for bone formation during development as well as during remodelling and repair in the adult skeleton. This results in a heavily vascularized tissue where endothelial cells and skeletal cells are constantly in crosstalk to facilitate homeostasis, a...

Full description

Bibliographic Details
Main Authors: N. Shen, M. Maggio, I. Woods, M. C. Lowry, R. Almasri, C. Gorgun, K.F. Eichholz, E. Stavenschi, K. Hokamp, F.M. Roche, L. O’Driscoll, D.A. Hoey
Format: Article
Language:English
Published: SAGE Publishing 2023-08-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231186918