Transport between im/mobile fractions shapes the speed and profile of cargo distribution in neurons

Neuronal function requires continuous distribution of ion channels and other proteins throughout large cell morphologies. Protein distribution is complicated by immobilization of freely diffusing subunits such as on lipid rafts or in postsynaptic densities. Here, we infer rates of immobilization for...

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Bibliographic Details
Main Authors: Adriano A. Bellotti, Jonathan G. Murphy, Timothy S. O’Leary, Dax A. Hoffman
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074722000398