Salidroside attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin-II through inhibition of LOXL2-TGF-β1-Smad2/3 pathway

Salidroside attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin-II through inhibition of LOXL2-TGF-β1-Smad2/3 pathway

Aims and objectives: Salidroside (SAL), an active component isolated from the Chinese plant Rose Rhodiola, has anti-inflammatory, antioxidant, anti-cancer, neuroprotective, and renal protective properties. Atrial fibrosis developed due to angiotensin II (Ang II) plays a crucial function in developin...

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Bibliographic Details
Main Authors: Zhen Hai, Yingbiao Wu, Zhongping Ning
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Salidroside
Atrial fibrillation
Atrial fibrosis
Angiotensin II
Lysyl oxidase-like 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023084281

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http://www.sciencedirect.com/science/article/pii/S2405844023084281

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