Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or ApoC3 RNA interference[S]

Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or ApoC3 RNA interference[S]

Dyslipidemia and insulin resistance are significant adverse outcomes of consuming high-sugar diets. Conversely, dietary fish oil (FO) reduces plasma lipids. Diet-induced dyslipidemia in a rhesus model better approximates the pathophysiology of human metabolic syndrome (MetS) than rodent models. Here...

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Bibliographic Details
Main Authors: Andrew A. Butler, Candice A. Price, James L. Graham, Kimber L. Stanhope, Sarah King, Yu-Han Hung, Praveen Sethupathy, So Wong, James Hamilton, Ronald M. Krauss, Andrew A. Bremer, Peter J. Havel
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Lipid Research
Subjects:
diet effects/lipid metabolism
nutrition/carbohydrate
nonhuman primate models
apolipoproteins
ribonucleic acid interference
lipogenic enzymes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520325943

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http://www.sciencedirect.com/science/article/pii/S0022227520325943

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