Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells

Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells

Sphingolipids are key signaling biomolecules that play a distinct role in cell proliferation, migration, invasion, drug resistance, metastasis, and apoptosis. Triple-negative (ER−PR−HER2−) and triple-positive (ER+PR+HER2+) breast cancer (called TNBC and TPBC, respectively) subtypes reveal distinct p...

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Bibliographic Details
Main Authors: Kajal Rajput, Mohammad Nafees Ansari, Somesh K. Jha, Trishna Pani, Nihal Medatwal, Somdeb Chattopadhyay, Avinash Bajaj, Ujjaini Dasgupta
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
breast cancer
sphingolipids
triple-negative breast cancer
triple-positive breast cancer
ceramide-1-phosphate
siRNA delivery
Online Access:https://www.mdpi.com/2072-6694/14/18/4496

Internet

https://www.mdpi.com/2072-6694/14/18/4496

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