A Potential Biomarker of Dynamic Change in Peripheral CD45RA<sup>−</sup>CD27<sup>+</sup>CD127<sup>+</sup> Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma

A Potential Biomarker of Dynamic Change in Peripheral CD45RA<sup>−</sup>CD27<sup>+</sup>CD127<sup>+</sup> Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma

In order to develop a biomarker predicting the efficacy of treatments for patients with esophageal squamous cell carcinoma (ESCC), we evaluated the subpopulation of T cells in ESCC patients treated with chemotherapy (CT), chemoradiotherapy (CRT), and nivolumab therapy (NT). Fifty-five ESCC patients...

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Bibliographic Details
Main Authors: Mei Sakuma, Kosaku Mimura, Shotaro Nakajima, Akinao Kaneta, Tomohiro Kikuchi, Azuma Nirei, Takeshi Tada, Hiroyuki Hanayama, Hirokazu Okayama, Wataru Sakamoto, Motonobu Saito, Tomoyuki Momma, Zenichiro Saze, Koji Kono
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
esophageal squamous cell carcinoma
biomarker
central memory T cell
PD-1
TIM-3
Online Access:https://www.mdpi.com/2072-6694/15/14/3641

Internet

https://www.mdpi.com/2072-6694/15/14/3641

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