Bone marrow mononuclear cells up-regulate toll-like receptor expression and produce inflammatory mediators in response to cigarette smoke extract.

Bone marrow mononuclear cells up-regulate toll-like receptor expression and produce inflammatory mediators in response to cigarette smoke extract.

Several reports link cigarette smoking with leukemia. However, the effects of cigarette smoke extract (CSE) on bone marrow hematopoiesis remain unknown. The objective of this study was to elucidate the direct effects of cigarette smoke on human bone marrow hematopoiesis and characterize the inflamma...

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Bibliographic Details
Main Authors: Junmin Zhou, Erika A Eksioglu, Nicole R Fortenbery, Xianghong Chen, Huaquan Wang, Pearlie K Epling-Burnette, Julie Y Djeu, Sheng Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3126797?pdf=render

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http://europepmc.org/articles/PMC3126797?pdf=render

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