Synthesis and Evaluation of Poly(3-hydroxypropyl Ethylene-imine) and Its Blends with Chitosan Forming Novel Elastic Films for Delivery of Haloperidol

Synthesis and Evaluation of Poly(3-hydroxypropyl Ethylene-imine) and Its Blends with Chitosan Forming Novel Elastic Films for Delivery of Haloperidol

This study aimed to develop novel elastic films based on chitosan and poly(3-hydroxypropyl ethyleneimine) or P3HPEI for the rapid delivery of haloperidol. P3HPEI was synthesized using a nucleophilic substitution reaction of linear polyethyleneimine (L-PEI) with 3-bromo-1-propanol. <sup>1</s...

Full description

Bibliographic Details
Main Authors: Sitthiphong Soradech, Pattarawadee Kengkwasingh, Adrian C. Williams, Vitaliy V. Khutoryanskiy
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
chitosan
poly(3-hydroxypropyl ethyleneimine)
polymer blend
elastic films
miscibility
haloperidol
Online Access:https://www.mdpi.com/1999-4923/14/12/2671

Internet

https://www.mdpi.com/1999-4923/14/12/2671

Similar Items