RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy

RNA-Seq–based transcriptome analysis of corneal endothelial cells derived from patients with Fuchs endothelial corneal dystrophy

Abstract Fuchs endothelial corneal dystrophy (FECD) is the most common inherited corneal disease. Fibrillar focal excrescences called guttae and corneal edema due to corneal endothelial cell death result in progressive vision loss. Multiple genetic variants have been reported, but the pathogenesis o...

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Bibliographic Details
Main Authors: Tatsuya Nakagawa, Yuichi Tokuda, Masakazu Nakano, Yuya Komori, Naoya Hanada, Theofilos Tourtas, Ursula Schlötzer-Schrehardt, Friedrich Kruse, Kei Tashiro, Noriko Koizumi, Naoki Okumura
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35468-y

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https://doi.org/10.1038/s41598-023-35468-y

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