Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry

Summary: SARS-CoV-2 continues to evolve into variants of concern (VOC), with greatest variability in the multidomain, entry-facilitating spike proteins. To recognize the significance of adaptive spike protein changes, we compare variant SARS-CoV-2 virus particles in several assays reflecting authent...

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Bibliographic Details
Main Authors: Enya Qing, Pengfei Li, Laura Cooper, Sebastian Schulz, Hans-Martin Jäck, Lijun Rong, Stanley Perlman, Tom Gallagher
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005538