SorCS3 promotes the internalization of p75NTR to inhibit GBM progression

SorCS3 promotes the internalization of p75NTR to inhibit GBM progression

Abstract Glioblastoma (GBM) is a fatal malignancy caused by dysregulation of cellular signal transduction. Internalization plays a key role in maintaining signalling balance. Previous reports showed that Sortilin related VPS10 domain containing receptor 3 (SorCS3) has the ability to regulate interna...

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Bibliographic Details
Main Authors: Yanqiu Zhang, Yue Li, Yuhua Fan, Xiaoyuan Zhang, Zhihong Tang, Jing Qi, Baoshan Zhao, Fuyuan Li, Xiaofeng Chen, Huan Liang, Haiyan Xu, Dongliang Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04753-5

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https://doi.org/10.1038/s41419-022-04753-5

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