Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions

<p>Abstract</p> <p>Background</p> <p>Epigenetics is the study of heritable changes in gene function that cannot be explained by changes in DNA sequence. One of the most commonly studied epigenetic alterations is cytosine methylation, which is a well recognized mechanism...

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Bibliographic Details
Main Authors: Wiemels Joseph, Nelson Heather H, Wrensch Margaret, Karagas Margaret R, Marsit Carmen J, Yeh Ru-Fang, Christensen Brock C, Houseman E Andres, Zheng Shichun, Wiencke John K, Kelsey Karl T
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/365