Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy

Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy

Abstract Invariant natural killer T (iNKT) cells are a subset of innate-like T cells restricted by a major histocompatibility complex (MHC) class I-like molecule, CD1d. iNKT cells express an invariant T cell receptor (TCR) encoded by Vα14 Jα18 in mice and Vα24 Jα18 in humans and are activated by rec...

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Bibliographic Details
Main Authors: Takahiro Aoki, Shinichiro Motohashi, Haruhiko Koseki
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Inflammation and Regeneration
Subjects:
iNKT cells
iPS cells (iPSCs)
Cancer immunotherapy
Innate immunity
Acquired immunity
Clinical trial
Online Access:https://doi.org/10.1186/s41232-023-00275-5

Internet

https://doi.org/10.1186/s41232-023-00275-5

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