Intracellular mannose binding lectin mediates subcellular trafficking of HIV-1 gp120 in neurons

Intracellular mannose binding lectin mediates subcellular trafficking of HIV-1 gp120 in neurons

Human immunodeficiency virus-1 (HIV-1) enters the brain early during infection and leads to severe neuronal damage and central nervous system impairment. HIV-1 envelope glycoprotein 120 (gp120), a neurotoxin, undergoes intracellular trafficking and transport across neurons; however mechanisms of gp1...

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Bibliographic Details
Main Authors: C. Teodorof, S. Divakar, B. Soontornniyomkij, C.L. Achim, M. Kaul, K.K. Singh
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neurobiology of Disease
Subjects:
Mannose binding lectin
Subcellular trafficking
HIV-1 gp120
Microtubule associated protein-2
Neuronal transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001120

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http://www.sciencedirect.com/science/article/pii/S0969996114001120

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