A randomized phase II study of acyclovir for the prevention of chemotherapy-induced oral mucositis in patients undergoing autologous hematopoietic stem cell transplantation

A randomized phase II study of acyclovir for the prevention of chemotherapy-induced oral mucositis in patients undergoing autologous hematopoietic stem cell transplantation

Abstract Objectives To prove our hypothesis that acyclovir prophylaxis in autologous hematopoietic stem cell transplantation (AHSCT) recipients with hematologic malignancies (HM) reduces the incidence of chemotherapy-induced oral mucositis (CIOM) by inhibiting the intraoral HSV reactivation during t...

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Bibliographic Details
Main Authors: Junshik Hong, Hee-Kyung Park, Sung-Ho Chang, Ja Min Byun, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon, Youngnim Choi, Inho Kim
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Oral Health
Subjects:
Oral mucositis
Herpes simplex virus
Autologous stem cell transplantation
Acyclovir
Chemotherapy
Online Access:https://doi.org/10.1186/s12903-023-03623-6

Internet

https://doi.org/10.1186/s12903-023-03623-6

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