Nonstructural Protein NS1 of Influenza Virus Disrupts Mitochondrial Dynamics and Enhances Mitophagy via ULK1 and BNIP3

Nonstructural Protein NS1 of Influenza Virus Disrupts Mitochondrial Dynamics and Enhances Mitophagy via ULK1 and BNIP3

Nonstructural protein 1 (NS1) of influenza virus (IFV) is essential for evading interferon (IFN)-mediated antiviral responses, thereby contributing to the pathogenesis of influenza. Mitophagy is a type of autophagy that selectively removes damaged mitochondria. The role of NS1 in IFV-mediated mitoph...

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Bibliographic Details
Main Authors: Jae-Hwan Lee, Soo-Jin Oh, Jeanho Yun, Ok Sarah Shin
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
influenza a virus
NS1
mitophagy
antiviral immune responses
BNIP3
Online Access:https://www.mdpi.com/1999-4915/13/9/1845

Internet

https://www.mdpi.com/1999-4915/13/9/1845

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