Novel interaction of properdin and coagulation factor XI: Crosstalk between complement and coagulation

Abstract Background Evidence of crosstalk between the complement and coagulation cascades exists, and dysregulation of either pathway can lead to serious thromboinflammatory events. Both the intrinsic pathway of coagulation and the alternative pathway of complement interact with anionic surfaces, su...

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Bibliographic Details
Main Authors: Samantha L. Heal, Lewis J. Hardy, Clare L. Wilson, Majid Ali, Robert A. S. Ariëns, Richard Foster, Helen Philippou
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12715