Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system

Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system

Abstract Background Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR associates with Nanog (a stem cell marker) and participates in OCSC fu...

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Bibliographic Details
Main Authors: Kaijian Ling, Lupin Jiang, Shi Liang, Joseph Kwong, Leiyan Yang, Yudi Li, PingYin, Qingchun Deng, Zhiqing Liang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Ovarian Research
Subjects:
Nanog
Androgen receptor signaling axis
Ovarian cancer
Stemness properties
Online Access:http://link.springer.com/article/10.1186/s13048-018-0403-2

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http://link.springer.com/article/10.1186/s13048-018-0403-2

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