Immediate early response 3 gene promotes aggressive progression and autophagy of AML by negatively regulating AKT/mTOR

Immediate early response 3 gene promotes aggressive progression and autophagy of AML by negatively regulating AKT/mTOR

Background: Immediate early response 3 (IER3) plays a vital role in many tumors. This study aims to explore the function and mechanism of IER3 in Acute myeloid leukemia (AML). Methods: The expression of IER3 in AML was performed by bioinformatics analysis. CCK-8 proliferation assay, flow cytometry c...

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Bibliographic Details
Main Authors: Yimin Chen, Zhenqian Huang, Shuyi Chen, Li Tan, Lang He, Danyun Yuan, Lixia Zheng, Jing hua Zhong, Anqiao Li, Heng Zhang, Huo Tan, Lihua Xu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Translational Oncology
Subjects:
IER3
acute myeloid leukemia
proliferation
autophagy
AKT/mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323000979

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http://www.sciencedirect.com/science/article/pii/S1936523323000979

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