The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

<h4>Background</h4>The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP. Considering its highly dynamic nature, the protein is rather stable. We studied the ther...

Full description

Bibliographic Details
Main Authors: Khanh K Dao, Angel L Pey, Anja Underhaug Gjerde, Knut Teigen, In-Ja L Byeon, Stein O Døskeland, Angela M Gronenborn, Aurora Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21394209/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21394209/pdf/?tool=EBI

Similar Items