Treatment of Brain Metastases: The Synergy of Radiotherapy and Immune Checkpoint Inhibitors

Treatment of Brain Metastases: The Synergy of Radiotherapy and Immune Checkpoint Inhibitors

Brain metastases are a devastating sequela of common primary cancers (e.g., lung, breast, and skin) and have limited effective therapeutic options. Previously, systemic chemotherapy failed to demonstrate significant benefit in patients with brain metastases, but in recent decades, targeted therapies...

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Bibliographic Details
Main Authors: Jennifer K. Matsui, Haley K. Perlow, Rohit K. Raj, Ansel P. Nalin, Eric J. Lehrer, Rupesh Kotecha, Daniel M. Trifiletti, Shearwood McClelland, Kari Kendra, Nicole Williams, Dwight H. Owen, Carolyn J. Presley, Evan M. Thomas, Sasha J. Beyer, Dukagjin M. Blakaj, Manmeet S. Ahluwalia, Raju R. Raval, Joshua D. Palmer
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
brain metastases
radiotherapy
radiation therapy
systemic therapy
immune checkpoint inhibitors
immunoradiotherapy
Online Access:https://www.mdpi.com/2227-9059/10/9/2211

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https://www.mdpi.com/2227-9059/10/9/2211

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