Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population

Objective: This study investigated the relationships of tumor status (stage, renal involvement, bone marrow status, bulky disease, liver function), tumor gene polymorphism, and methotrexate (MTX) dosage (stratified by treatment group) with blood MTX levels and adverse reactions (ADR). Methods: We re...

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Bibliographic Details
Main Authors: Shuang Huang, Lin Jin, Jing Yang, Long Yan Duan, Meng Zhang, Ju Chun Zhou, Hong Yong Zhang
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/1533033821995288