A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

Extracellular vesicles (EVs) are emerging mediators of intercellular communication in nonalcoholic steatohepatitis (NASH). Palmitate, a lipotoxic saturated fatty acid, activates hepatocellular endoplasmic reticulum stress, which has been demonstrated to be important in NASH pathogenesis, including i...

Full description

Bibliographic Details
Main Authors: Yasuhiko Nakao, Masanori Fukushima, Amy S. Mauer, Chieh-Yu Liao, Anya Ferris, Debanjali Dasgupta, Carrie Jo Heppelmann, Patrick M. Vanderboom, Mayank Saraswat, Akhilesh Pandey, K. Sreekumaran Nair, Alina M. Allen, Kazuhiko Nakao, Harmeet Malhi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
exosome
microvesicle
DAMP
hepatocyte
StAR-related lipid transfer domain 11
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.735001/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.735001/full

Similar Items