Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC

Abstract Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer and is associated with poor prognosis. The histone H3 lysine 36 methyltransferase SET-domain-containing 2 (SETD2) has been reported to be expressed at low levels and frequently mutated in ccRCC. Ferroptosis,...

ver descrição completa

Detalhes bibliográficos
Principais autores: Wei Xue, Wengang Jian, Yuyang Meng, Tengda Wang, Licheng Cai, Yongchun Yu, Yipeng Yu, Zhinan Xia, Cheng Zhang
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2023-08-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-023-06057-8