RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells

RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells

Fanconi anemia complementation group F protein (FANCF) is a key factor, which maintains the function of FA/BRCA, a DNA damage response pathway. However, the functional role of FANCF in breast cancer has not been elucidated. We performed a specific FANCF-shRNA knockdown of endogenous FANCF in vitro....

Full description

Bibliographic Details
Main Authors: L. Zhao, N. Li, J.K. Yu, H.T. Tang, Y.L. Li, M. He, Z.J. Yu, X.F. Bai, Z.H. Zheng, E.H. Wang, M.J. Wei
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Fanconi anemia complementation group F protein
Breast neoplasms
Tumor cell line
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000100024&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000100024&lng=en&tlng=en

Similar Items