Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
Abstract Background Genetic diversity is known to confer survival advantage in many species across the tree of life. Here, we hypothesize that such pattern applies to humans as well and could be a result of higher fitness in individuals with higher genomic heterozygosity. Results We use healthy agin...
Main Authors: | Ke Xu, Roman Kosoy, Khader Shameer, Sudhir Kumar, Li Liu, Ben Readhead, Gillian M. Belbin, Hao-Chih Lee, Rong Chen, Joel T. Dudley |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Genetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12863-019-0758-4 |
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