Soft Tissue Sarcoma Study: Association of Genetic Alterations in the Apoptosis Pathways with Chemoresistance to Doxorubicin

Soft Tissue Sarcoma Study: Association of Genetic Alterations in the Apoptosis Pathways with Chemoresistance to Doxorubicin

Soft tissue sarcomas (STS) are heterogeneous cancers with more than 100 histological subtypes, different in molecular alterations, which make its personalized therapy very complex. Gold standard of chemotherapy for advanced STS includes combinations of Doxorubicin and Ifosfamide or Gemcitabine and D...

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Bibliographic Details
Main Authors: Evgeny M. Kirilin, Timur I. Fetisov, Natalia I. Moiseeva, Ekaterina A. Lesovaya, Lidia A. Laletina, Leyla F. Makhmudova, Angelika E. Manikaylo, Liliya Y. Fomina, Denis A. Burov, Beniamin Yu. Bokhyan, Victoria Y. Zinovieva, Alice S. Vilkova, Larisa V. Mekheda, Nikolay A. Kozlov, Alexander M. Scherbakov, Gennady A. Belitsky, Vytas Švedas, Kirill I. Kirsanov, Marianna G. Yakubovskaya
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
soft tissue sarcoma
undifferentiated pleomorphic sarcoma
synovial sarcoma
chemoresistance
Doxorubicin
Ifosfamide
Online Access:https://www.mdpi.com/2072-6694/14/7/1796

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https://www.mdpi.com/2072-6694/14/7/1796

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