Stochastic palmitoylation of accessible cysteines in membrane proteins revealed by native mass spectrometry
Cysteine palmitoylation affects the localization and function of membrane proteins, but its stoichiometry and specificity are not well understood. Here, the authors show that palmitoylation is a stochastic process that depends on the accessibility of cysteines rather than a defined substrate motif.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01461-z |