Dapagliflozin has No Protective Effect on Experimental Pulmonary Arterial Hypertension and Pulmonary Trunk Banding Rat Models

Dapagliflozin has No Protective Effect on Experimental Pulmonary Arterial Hypertension and Pulmonary Trunk Banding Rat Models

Sodium-glucose cotransporter-2 (SGLT2) inhibitors, a novel class of hypoglycemic drugs, show excellent cardiovascular benefits, and have further improved heart failure outcomes, significantly reducing cardiovascular and all-cause mortality irrespective of diabetes status. However, the efficacy of SG...

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Bibliographic Details
Main Authors: Huayang Li, Yitao Zhang, Shunjun Wang, Yuan Yue, Quan Liu, Suiqing Huang, Huajing Peng, Yi Zhang, Weijie Zeng, Zhongkai Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
pulmonary trunk banding
pulmonary vascular remodeling
right ventricular dysfunction
SGLT2 inhibitors
dapagliflozin
pulmonary arterial hypertension
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.756226/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.756226/full

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