Cell Cycle Inhibition To Treat Sleeping Sickness

Cell Cycle Inhibition To Treat Sleeping Sickness

ABSTRACT African trypanosomiasis is caused by infection with the protozoan parasite Trypanosoma brucei. During infection, this pathogen divides rapidly to high density in the bloodstream of its mammalian host in a manner similar to that of leukemia. Like all eukaryotes, T. brucei has a cell cycle in...

Full description

Bibliographic Details
Main Authors: Conrad L. Epting, Brian T. Emmer, Nga Y. Du, Joann M. Taylor, Ming Y. Makanji, Cheryl L. Olson, David M. Engman
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Subjects:
African sleeping sickness
Trypanosoma brucei
hydroxyurea
ribonucleotide reductase
Online Access:https://journals.asm.org/doi/10.1128/mBio.01427-17

Internet

https://journals.asm.org/doi/10.1128/mBio.01427-17

Similar Items