Single subanesthetic dose of ketamine produces delayed impact on brain [18F]FDG PET imaging and metabolic connectivity in rats

Single subanesthetic dose of ketamine produces delayed impact on brain [18F]FDG PET imaging and metabolic connectivity in rats

IntroductionKetamine, a glutamate NMDA receptor antagonist, is suggested to act very rapidly and durably on the depressive symptoms including treatment-resistant patients but its mechanisms of action remain unclear. There is a requirement for non-invasive biomarkers, such as imaging techniques, whic...

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Bibliographic Details
Main Authors: Sarah Chaib, Caroline Bouillot, Sandrine Bouvard, Benjamin Vidal, Luc Zimmer, Elise Levigoureux
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neuroscience
Subjects:
ketamine
FDG
PET
metabolic connectivity
neuroimaging
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1213941/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1213941/full

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