SPACR Encoded by <i>IMPG1</i> Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium

SPACR Encoded by <i>IMPG1</i> Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium

Several pathogenic variants have been reported in the <i>IMPG1</i> gene associated with the inherited retinal disorders vitelliform macular dystrophy (VMD) and retinitis pigmentosa (RP). <i>IMPG1</i> and its paralog <i>IMPG2</i> encode for two proteoglycans, SPACR...

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Bibliographic Details
Main Authors: Guillaume Olivier, Philippe Brabet, Nelly Pirot, Morgane Broyon, Laurent Guillou, Chantal Cazevieille, Chamroeun Sar, Melanie Quiles, Emmanuelle Sarzi, Marie Pequignot, Ervann Andreo, Agathe Roubertie, Isabelle Meunier, Agnès Muller, Vasiliki Kalatzis, Gaël Manes
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Genes
Subjects:
<i>IMPG1</i>
<i>IMPG2</i>
SPACR
SPACRCAN
vitelliform macular dystrophy
retinitis pigmentosa
Online Access:https://www.mdpi.com/2073-4425/13/9/1508

Internet

https://www.mdpi.com/2073-4425/13/9/1508

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