A Comparative Study of Tumor-Specificity and Neurotoxicity between 3-Styrylchromones and Anti-Cancer Drugs

A Comparative Study of Tumor-Specificity and Neurotoxicity between 3-Styrylchromones and Anti-Cancer Drugs

<b>Background.</b> Many anti-cancer drugs used in clinical practice cause adverse events such as oral mucositis, neurotoxicity, and extravascular leakage. We have reported that two 3-styrylchromone derivatives, 7-methoxy-3-[(1<i>E</i>)-2-phenylethenyl]-4<i>H</i>-1...

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Bibliographic Details
Main Authors: Tomoyuki Abe, Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-ichi Tanuma, Hiroshi Takeshima
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Medicines
Subjects:
chromone derivatives
oral squamous cell carcinoma
tumor-specificity
keratinocyte toxicity
neurotoxicity
signaling pathway
Online Access:https://www.mdpi.com/2305-6320/10/7/43

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https://www.mdpi.com/2305-6320/10/7/43

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