Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

Abstract Purpose Multiple genome-wide and candidate-gene association studies have been conducted to search for common risk variants of breast cancer. Recent large meta-analyses and consolidating evidence have highlighted the role of the caspase-8 gene in breast cancer pathogenesis. Therefore, this s...

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Bibliographic Details
Main Authors: Fahimeh Afzaljavan, Elham Vahednia, Matineh Barati Bagherabad, Fatemeh Vakili, Atefeh Moezzi, Azar Hosseini, Fatemeh Homaei Shandiz, Mohammad Mahdi Kooshyar, Mohammadreza Nassiri, Alireza Pasdar
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Medical Genomics
Subjects:
Breast neoplasm
Biomarker
Caspase 8
Diplotype
Overall survival
Prognosis
Online Access:https://doi.org/10.1186/s12920-023-01484-0

Internet

https://doi.org/10.1186/s12920-023-01484-0

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