A Double-Negative Feedback Interaction between miR-21 and PPAR-α in Clear Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) is the main histotype of kidney cancer, which is typically highly resistant to conventional therapies and known for abnormal lipid accumulation. In this context, we focused our attention on miR-21, an oncogenic miRNA overexpressed in ccRCC, and peroxysome prol...

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Bibliographic Details
Main Authors: Marine Goujon, Justine Woszczyk, Kelly Gaudelot, Thomas Swierczewski, Sandy Fellah, Jean-Baptiste Gibier, Isabelle Van Seuningen, Romain Larrue, Christelle Cauffiez, Viviane Gnemmi, Sébastien Aubert, Nicolas Pottier, Michaël Perrais
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/3/795