Serum short chain fatty acids mediate hippocampal BDNF and correlate with decreasing neuroinflammation following high pectin fiber diet in mice

Serum short chain fatty acids mediate hippocampal BDNF and correlate with decreasing neuroinflammation following high pectin fiber diet in mice

IntroductionDietary components, such as prebiotic fiber, are known to impact brain chemistry via the gut-brain axis. In particular, short chain fatty acids (SCFAs) generated from excessive soluble fiber consumption are thought to impact neuroimmune signaling and brain function through increased prod...

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Bibliographic Details
Main Authors: Jamie S. Church, Jane A. M. Bannish, Leighelle A. Adrian, Kimberly Rojas Martinez, Asari Henshaw, Jared J. Schwartzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neuroscience
Subjects:
pectin fiber
diet
SCFAs
BDNF
hippocampus
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1134080/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1134080/full

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